An international journal published by the Nigerian Society for Experimental Biology Printed in Nigeria Cofactor interactions in the activation of tissue non-specific alkaline phosphatase: Synergistic effects of Zn2+ and Mg2+ ions Femi J. OLORUNNIJI*‚ Adedoyin IGUNNU‚ Joseph O. ADEBAYO‚ Rotimi O. ARISE and Sylvia O. MALOMO Department of Biochemistry‚ University of Ilorin‚ P.M.B. 1515 Ilorin‚ Nigeria Received 19 March 2007 MS/No BKM/2007/028‚ © 2007 Nigerian Society for Experimental
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Hypophosphatasia is one of many disorders that resemble oseogenisis imperfecta‚ also known as “Brittle Bone Disease”. A mutation in the gene that codes for tissue-nonspecific alkaline phosphatase‚ or ALP‚ is believed to be the cause. That is the central hostile regulator for bone mineralization. The patient who has Hypophosphatasia receives one defective gene from each parent. (Hypophosphatasia‚ eMedicine) Males‚ females‚ and all races are equally affected. Incidence has been rated
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Division of City Schools City of Mandaluyong Science High School E. Pantaleon St. Hulo‚ Mandaluyong City BLACK MIX FROM ALKALINE BATTERIES AS PIGMENT FOR THE MANUFACTURE OF INKJET PRINTER-FRIENDLY INK Submitted in partial fulfilment of the requirements in Research II By Psalm Israel Rendon Hazel A. Lunas Diane Clarisse Ortega IV-Chlorine SY 2011 -2012 September 2011 TABLE OF CONTENTS TITLE PAGE.........................................................................
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tests were used to determine significant differences among groups. P < 0.05 was considered to be significant. 6.3 Results 6.3.1 Liver function tests Liver toxicity markers were assayed to assess hepatic injury. The activities of alkaline phosphatase (ALP)‚ acid phosphatase (ACP) and gamma glutamyl transferase (GGT) were significantly altered in the diabetic control group‚ indicating damage to hepatocytes. The hepatic toxicity markers in normal rats treated with ABE did not show any significant difference
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J.L. SOAP NOTE Subjective J.L. is a 63-year-old white female who presented to the ER with right lower extremity pain and swelling with subsequent changes to the skin‚ including formation of bullous ulcers. She had blistering over the past four days that started to enlarge. The doctor prescribed her Bactrim. Erythema‚ swelling‚ and pain progressively got worse. She denies any fever or chills. PMH: COPD‚ Hypertension‚ Diabetes mellitus‚ Osteoporosis‚ Fibromyalgia‚ Osteoarthritis‚ Morbid obesity
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ALKALINE EARTH METALS what are alkaline earth metals? Alkaline earth metals are elements that are in the second group of the periodic table. the elements have two electrons on the outermost shell. the elements include Beryllium‚ magnesseum‚ calcium‚strontium‚ barium and Radium.The alkaline earth metals are all silvercolored and soft‚ and have relatively low densities‚ melting points‚ and boiling points. In chemical terms‚ all of the alkaline metals react with the halogens to form the alkaline earth metal halides
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Laboratory# 26 Group 2: The Alkaline Earth Metals Period E Bautista‚ Angel Table D Comer‚ Tyler 3/22/12 Sullivan‚ Brittany Truong‚ Phuoc Conclusions and Questions 1. Step 1: Ca(s) +H2O->Ca (OH)2(aq)+H2(g) Step 4: Mg(s) +H2O->Mg (OH)2(aq)+H2(g) Step 10: CaSO4 + H2O-> Ca(OH)2 + H2SO4 MgSO4 + H2O ->Mg (OH)2 + H2SO4 Barium Sulfate: No reaction Step 13: MgCl2 + Na2CO3 -> MgCO3 + 2NaCl CaCl2 + Na2CO3 -> CaCO3 + 2NaCl
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References: 1. Yamagata A‚ Kristensen DB‚ Takeda Y‚ Miyamoto Y‚ Okada K‚ Inamatsu M‚ Yoshizato K (2002) Mapping of phosphorylated proteins on two-dimensional polyacrylamide gels using protein phosphatase. Proteomics 2: 1267-1276. 2. Sun J‚ Morgan M‚ Shen R-F‚ Steenbergen C and Murphy E (2007) Preconditioning Results in S-Nitrosylation of Proteins Involved in Regulation of Mitochondrial Energetics and Calcium Transport. Circ Res 101: 1155-1163. 4
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Alkaline Phosphatase was isolated using various techniques. BCIP spot test was performed after the anion exchange chromatography was done and the fractions were collected. The picture of BCIP spot test of the 20 fractions can be seen in figure 1. The intensity of each spot was different from each other. The more intense color the spot was‚ the more concentrate the AP was. The fractions were chosen to combine together based on the intensity‚ which made the stage 4 enzyme. Different volumes in each
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Marine organisms: Potential source for drug discovery. Life has originated from the oceans that cover over 70% of the earth’s surface and contain highly ecological‚ chemical and biological diversity starting from microorganisms to vertebrates. This diversity has been the source of unique chemical compounds‚ which hold tremendous pharmaceutical potential. New trends in drug discovery from natural sources emphasize on investigation of the marine ecosystem to explore numerous complex and novel chemical
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