Quinoline Research Paper
In the past few years, antimicrobial compounds with quinoline moiety have drawn great attention from the point of pharmaceutical importance. Moreover many natural and synthetic, biologically active compounds that have nitrogen containing heterocycles and they constitute an important class of pharmacophores in medicinal chemistry [1-4]. Quinoline derivatives have been associated with anti-bacterial [5], antifungal and antitubercular [6-8], anti-cancer [9] activities, DNA binding capability [10] and have diverse biological applications. Nitroxoline (8-Hydroxy-5-Nitroquinoline) is a highly effective drug commonly used for urinary tract infections (pyelonephritis, cystitis urethritis, prostatitics etc.) with good localized action on infected site,