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Pathophysiology: Chronic Pyelonephritis

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Pathophysiology: Chronic Pyelonephritis
Pathophysiology Infection and inflammation of the kidneys is called pyelonephritis. Pyelonephritis is a type of urinary tract infection. E. coli is the most common microbe that causes pyelonephritis. It usually begins in the urethra or bladder and travels to the kidneys. There is a chance of it spreading to the calyces and medullary tissues such as the tubules of the nephrons. If not treated the glomeruli will also be infected and inflamed. (Bullock & Hales 2013).
There is both acute pyelonephritis and chronic pyelonephritis. In acute pyelonephritis, phagocytes and inflammatory exudate travel to the infected area blocking tubule function during acute pyelonephritis. Chronic forms of the condition are more common in people with urinary obstructions. UTIs, vesicoureteral reflux, or anatomical anomalies can all be contributing factors to chronic pyelonephritis. Chronic pyelonephritis is more common in children than in adults. Women are also at a
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A dipstick is used to test urine and a midstream specimen of urine (MSU) sample is collected and sent to the labs for examination and culture. If the person seems to be having sepsis and showing fever, blood is drawn for labs. White blood cells and neutrophils elevation are likely results. If a negative result occurs, infection is not automatically ruled out. A false negative can happen in situations where an antibiotic treatment has started. An intravenous pyelogram, ultrasound, or CT scan may be needed if other causes of diseases need to be excluded. In addition to the tests, a medical history and physical assessment will help find the diagnosis (Bullock & Hales 2013). The patient’s labs such as low Hgb (7.3), Hct (22.8), Rbc (2.52), WBC (3.0), BUN (39), Creatinine (1.3) show signs that she has kidney disease. She is also experiencing the symptoms such as right hip pain and lower back pain which is consistent with

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