It is classified as Class II drug with low solubility and high permeability properties. Due to its very poor solubility in acidic pH of the stomach, it remains in the stomach wall for a long period, aggravating its potential side effects (peptic ulcers and gastric irritation) (5).
Immediate release (IR) oral dosage forms, i.e., tablets and capsules, are designed to disintegrate in the stomach followed by their dissolution in the fluids of the gastrointestinal …show more content…
Tablets containing liquid dissolution modulators (Liquitablets) are often prepared using direct compression technique with the aid of suitable carrier and coating materials. In our work, according to our knowledge, it is the first time to prepare liquitablets using blister molding method. Blister molding technique is a simple, easily scalable and requires no special equipment compared to the conventional