Ebola Case Study
1) How might the binding of a molecule bound to the surface of Cell A be connected to the intracellular phosphorylation of protein Y in Cell B? (10 pts)
Cell A and Cell B interact with each other through receptor-ligand or receptor-receptor interactions. To be specific, through the receptor-ligand interaction, Cell A deliver signals to Cell B by triggering the signal transduction pathways in Cell B which mediated by small molecules or proteins. The signal transduction pathways including the intracellular phosphorylation, which can activate the cell signaling.
2) Why were public health officials concerned in Minneapolis about an Ebola epidemic in Liberia? What was the response? (10 pts)
Because the infectious diseases such as Ebola could be …show more content…
epidermis a good thing to have on the skin? (10 pt)
Because Staph. the epidermis is a kind of commensals on the skin, which protects the skin from getting infected. They have three main functions on the skin, the first is to prevent colonization by pathogenic strains because they limit the space for other pathogens, the second is that they produce vitamins, finally, it also helps in metabolism.
6) Who does dsRNA interact with Toll Receptor 3 and why is it found in the endosome? (10 pt)
Pieces of pathogens (particularly pieces of viruses) do dsRNA interact with TLR-3. Because the pathogens (viruses) are destroyed into pieces in the endosome, after they are destroyed, they are mainly nucleic acid, such as dsRNA.
7) Why would the ability of a strain of Staph aureus to excrete a protease that destroys Toll receptors contribute to the lethality of the strain? (10 pt)
When pathogens such as Staph aureus are bound to toll receptors, it induces increasing in immune cells and activates several immune pathways such as inflammation and cell death. If the Staph aureus could excrete a protease that destroys Toll receptors, that toll receptors cannot induce the inflammatory response, which leads to the cell death of the bacterial
Cell A and Cell B interact with each other through receptor-ligand or receptor-receptor interactions. To be specific, through the receptor-ligand interaction, Cell A deliver signals to Cell B by triggering the signal transduction pathways in Cell B which mediated by small molecules or proteins. The signal transduction pathways including the intracellular phosphorylation, which can activate the cell signaling.
2) Why were public health officials concerned in Minneapolis about an Ebola epidemic in Liberia? What was the response? (10 pts)
Because the infectious diseases such as Ebola could be …show more content…
epidermis a good thing to have on the skin? (10 pt)
Because Staph. the epidermis is a kind of commensals on the skin, which protects the skin from getting infected. They have three main functions on the skin, the first is to prevent colonization by pathogenic strains because they limit the space for other pathogens, the second is that they produce vitamins, finally, it also helps in metabolism.
6) Who does dsRNA interact with Toll Receptor 3 and why is it found in the endosome? (10 pt)
Pieces of pathogens (particularly pieces of viruses) do dsRNA interact with TLR-3. Because the pathogens (viruses) are destroyed into pieces in the endosome, after they are destroyed, they are mainly nucleic acid, such as dsRNA.
7) Why would the ability of a strain of Staph aureus to excrete a protease that destroys Toll receptors contribute to the lethality of the strain? (10 pt)
When pathogens such as Staph aureus are bound to toll receptors, it induces increasing in immune cells and activates several immune pathways such as inflammation and cell death. If the Staph aureus could excrete a protease that destroys Toll receptors, that toll receptors cannot induce the inflammatory response, which leads to the cell death of the bacterial