AP2 Unit 3 discussion on Organ Transplantion
In this unit’s readings contained information about the four varieties of grafts. They are and definition are as follows: Autografts which is a transplant procedure where one 's own tissue is used to grafts for burns and plastic surgery. Isograft is a procedure where tissue from an identical twin is used for a tissue transplant. Allograft is a procedure where tissue from different genetic donor but is the same species as the recipient. Xenograft is a procedure where tissue of a different species such as pigs or cows are used on humans for severe burns.
2. Describe how and why both types of adaptive immunity can cause problems with organ transplantation.
Both types of adaptive immunity can cause problems with transplanted organs because they are systems created to help maintain homeostasis within the body. Cytotoxic T cells are part of the cell - mediated type of adaptive immunity. These cells are activated when specific foreign cells are detected in the body. They are cells that directly attack invading antigens within the body. (Tortora, 2014) Antibody-mediated immunity contains B cells that transforms into plasma membrane that synthesizes and secretes antibodies that bind to and deactivate specific antigens in the bodies fluids. (Tortora, 2014) An organ transplant cells usually is recognized in the body as non-self or foreign and provokes the adaptive immunity to respond with antigen fighting cells and plasma. Because both types work together to fight of antigens, they both can be troublesome for a transplant recipient ability to heal. (Tortora, 2014)
3. Discuss how the body works to recognize your own cells and to differentiate them from foreign body cells.
The body is able to recognize its own cells and differentiate them from foreign cells by developing self-recognition and self-tolerance during the developmental generation of the B and T cells. (Tortora, 2014) There are two processes that take place during the development of the B and T cells,
2. Describe how and why both types of adaptive immunity can cause problems with organ transplantation.
Both types of adaptive immunity can cause problems with transplanted organs because they are systems created to help maintain homeostasis within the body. Cytotoxic T cells are part of the cell - mediated type of adaptive immunity. These cells are activated when specific foreign cells are detected in the body. They are cells that directly attack invading antigens within the body. (Tortora, 2014) Antibody-mediated immunity contains B cells that transforms into plasma membrane that synthesizes and secretes antibodies that bind to and deactivate specific antigens in the bodies fluids. (Tortora, 2014) An organ transplant cells usually is recognized in the body as non-self or foreign and provokes the adaptive immunity to respond with antigen fighting cells and plasma. Because both types work together to fight of antigens, they both can be troublesome for a transplant recipient ability to heal. (Tortora, 2014)
3. Discuss how the body works to recognize your own cells and to differentiate them from foreign body cells.
The body is able to recognize its own cells and differentiate them from foreign cells by developing self-recognition and self-tolerance during the developmental generation of the B and T cells. (Tortora, 2014) There are two processes that take place during the development of the B and T cells,
References: Tortora, G. (2014). Principles of Anatomy and Physiology [VitalSouce bookshelf version]. Retrieved from http://online.vitalsource.com/books/9781118934678/id/P22-190 on September 14, 2014 Edward, Lin (2011). Phys.Org. Skin-cell gun drastically cut healing time for burns. Retrieved from http://phys.org/news/2011-02-skin-cell-gun-drastically.html on September 14, 2014 Medlinplus (2014). Immune Response, Retrieved from http://www.nlm.nih.gov/medlineplus/ency/article/000821.htm on September 16, 2014 Neuralstem Inc. (2014). Neuralstem Cell Therapy for ALS, Retrieved for http://www.neuralstem.com/cell-therapy-for-als on September 16, 2014. (Tortora, 2014) lo Class.