Active ingredient: Hydrochloric Acid Trade name: Lysol Brand Disinfectant Toilet Bowl Cleaner‚ Stain Fighter Manufacturer’s name: Reckitt Benckiser‚ Inc. Toxic Effects: irritation of the nasopharynx‚ burns on the skin and eyes‚ andblindness; chronic exposure causes tooth discoloration‚ dermatitis‚ and sensitivity to light. Individuals who ingest the substance have coughing‚ vomiting‚ chest pain‚ shortness of breath‚ and burns of the esophagus and stomach. Antidotes: Treatment involves removal
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API PRESENTATTION Some Definitions- Active Pharmaceutical Ingredient (API): A substance or compound that is intended to be used in the manufacture of a pharmaceutical product as a therapeutically active compound (ingredient) Enantiomers: cpds with same molecular formula as substance but differ in spatial arrangement of atoms and are non-superimpossable mirror images Polymorphism: Occurrence of different crystalline forms of the same substance Degradation product : Molecule resulting
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Sasha Thiel 09.10.2012 CH203 Lab Experiment 1: Isolation of the Active Ingredient in an Analgesic Drug Pre-Lab: A. Least accurate to most accurate 1. Beakers (5ml markings) 2. 10ml graduated cylinder (0.1 markings) 3. 5ml vials (0.1 and 0.3 markings) 4. 1ml plastic pipets (0.1 ml markings) 5. 1ml syringes (0.1 ml markings) 6. 1ml graduated volumetric pipets (0.01 ml markings) B. A 1ml graduated volumetric pipet is the best to use if you want 0.15 ml of reactant
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Isolation of the active ingredient in an Analgesic Drug from extraction‚ filtration and melting point. Chm237 Abstract: Acetaminaphen was crushed then extracted for the active ingredient by mixing it with methanol. Then separated from the binders by centrifugation and a filtration technique using a Pasteur pipet packed with alumina. The remaining solvent was then evaporated to yield the solid analgesic(.2295g‚ 45.9% yield) which was collected by filtration and tested for the
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INTRODUCTION: Penicillin is the basis for most of the antibiotics in the world just as aspirin is the basis for many drugs. Therefore‚ if there had been only two drugs to invent‚ it would be down to penicillin and aspirin. Hippocrates‚ the father of modern medicine lived sometime between 460 B.C and 377 B.C. Hippocrates has left historical records of pain relief treatments‚ including the use of a powder made from the bark and leaves of the willow tree to help heal headaches‚ pains and fevers.
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effects for some people‚ yet it is safe enough to be sold without a prescription. Because it is easy to prepare‚ aspirin is one of the most inexpensive drugs available. It is produced in vast amounts. In fact‚ industry makes 43‚000‚000 pounds of the drug every year. This microscale experiment will permit you to make an amount of aspirin equivalent to about 1/2 of that found in an aspirin tablet. Purpose: To synthesize acetylsalicylic acid on a microscale basis. Equipment / Materials: |salicylic
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Abstract For the amount of aspirin in a commercial tablet to be determined‚ different solutions of acetylsalicylic acid mixed with NaOH were created at different concentrations. All the different solutions were then analysed using Novaspec photometer‚ which allowed for a graph to be created and a line of best fit to be made. The amount of aspirin in a commercial tablet was found to be 350mg. Introduction The molecular formula for aspirin‚ also known as acetylsalicylic acid‚ is C9H8O4. It is most
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Introduction: The purpose of this lab was to learn how to use salicylic acid to make aspirin. Aspirin is the most widely used over-the-counter drug in the world. The average tablet contains about 325 milligrams of acetylsalicylic acid with an inert binding material such as starch. Aspirin is used to relieve pain‚ reduce inflammation‚ and lower fever. Aspirin originally was derived by boiling the bark of the white willow tree. Although the salicin in willow bark has analgesic properties‚ purified
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objective was to convert a specific amount of salicylic acid into the same amount of aspirin that was high in purity. Furthermore‚ the other objectives were to enable students to conduct the synthesis of aspirin‚ reinforce skills or recrystallisation and the technique of melting point determination. The amount of each compound should be the same because there is a 1:1 ratio between them. The purity of the synthesized aspirin was measured by determining its melting point and percent yield. Soluble impurities
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Aspirin or acetylsalicylate acid is a compound that is widely used in medicine. The use of aspirin in medicine began long before the active reagent was removed from its natural source. The first documented use of aspirin was found in the writings of Hippocrates‚ the so called father of medicine. Hippocrates prescribed that willow bark could be used to remedy a wide range of conditions such as pain‚ fever and inflammation. Scientists began to seek to extract the active compound from willow tree bark
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