Notable examples are quinine from Cinchona pubescens, reserpine from Rauwolfia serpentine and taxol from Taxus species. The sequence for development and formulation of pharmaceuticals usually starts with the identification of lead molecule, bioassay and then formulation into suitable dosage form. Later, this is authenticated by several phases of clinical studies designated to establish safety, purity, efficacy and pharmacokinetic profile of the new drug. During the last few decades, there has been a tremendous interest in plants as best source of medicines and of novel molecules for use in the elucidation of physiological/biochemical phenomena. There is worldwide green revolution, which is revealed in the confidence that herbal remedies are safer and less damaging and toxic to the human body than many of the synthetic drugs. Still, initially this growth of interest in plants is based on the fact that many important and useful drugs in use today are derived from starting molecules of plant origin. Laboratories around the world are seriously engaged in the screening the plants for significant biological activity with recognisable therapeutic…
My interest in this area was first aroused during my undergraduate studies at Bayero University, Kano (a Nigerian University) where I studied Chemistry and I chose to do my final year research on the topic “Extraction and Qualitative Analysis of Alkaloids from the Leaves, Seed and Flesh of Mangifera Indica”. During my research I sourced documents relating to Pharmacology and my interest was further aroused when reading some other documents relating to Organic and Medicinal Chemistry.…
Marijuana is known as a psychoactive drug made from flowers and dried leaves of the…
Cannabis Sativa (marijuana) has been around for thousands of years. It’s a plant that grows native to Africa and Asia. But it has been exported all over the world and used for its physcoative ingredients known as THC. The THC gives you a feeling of being high and is now illegal is the single most used elicit substance on the planet today. (Wikipedia)…
Early plant derivative anesthetics range from: mandrake, henbane, and Datura and were utilized to numb the area in which to be treated (Fischer, 2011). In the thirteenth century, these derivatives…
The leafy green plant appears quite harmless when we observe it in its natural environment. But, at times this very plant becomes of crucial importance for a drug addict as well as for a medical specialist. On the one hand the marijuana produced is inhaled by the drug addict to gaining a sense of relaxation, and heightening the senses. But for medical specialists this drug can do wonders for the health of patients with psychological disorders, for relieving pain for cancer patients or for stimulating appetite in the sick (BBC, 2008). Marijuana contains delta-9-tetrahydrocannabinol (or THC) as the main active chemical. It is considered as one of the most commonly abused drug in US with people smoking it as a cigarette or a pipe (NIDA,…
and buds primarily of the female cannabis plant. The plant also contains more than 500 other…
Natural Herbal Extracts Kwao Krua Dang ( Butea Superba) Male Menopause (Andropause): The reduction of male sex hormones Chemical Constituents from Butea Superba When age increasing, the male’s hormones i.e. Testosterone and Dehydroepiandrosterone will gradually decreasing unlike female menopause.…
This magical herb is very poorly portrayed in today’s society. Often referred to as “the Gateway Drug,” many people are ignorant as to the actual effects of the herb, as well as its many potential…
Various known plants in the Philippines are considered as weeds. One of which is the Tithonia diversifolia that is commonly known as Wild Sunflower. While it is considered as wild plant, it is also recognized for its significant uses in poultry, agricultural industry and pesticide industry and medicine.…
Cannabis sativa is a drug that is commonly known by people with the name marijuana. The legalization of marijuana has been considered as one of the most controversial issues that are prevailing all over the globe. In the United States, a lot of debate keeps focuses on the issue whether or not marijuana should be legalized or not. The Chinese writings that date back from the 2700B.C. document the use of weed for medicine (Researchomatic)…
References: 1) "Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants" Jose Luis Diaz M.D. Journal of Psychedelic Drugs Vol. 11 (1-2) Jan-Jun 1979…
Marijuana is a drug that is derived from the dried and cut leaves of the hemp plant known as "cannabis sativa". Marijuana has a variety of street names such as "grass", "Mary Jane", "pot", "smoke", "reefer", "herb", and "weed". The active ingredient in marijuana is delta tetrahydrocannabinol (THC). Marijuana has been used throughout history and in many different cultures to change mood, perception, and consciousness (to get "high"). Its effects range from increasing creativity to provoking mystical experiences, to heightening the capacity to feel, sense and share. After alcohol, it is the most popular of what are called "recreational drugs." It has been used around the world for other purposes. In some primitive tribes of South America, Africa, and India, "cannabis" is used in religious ceremonies and for medical purposes. African mine workers have used it to ease the drudgery of their work and many Jamaicans use it at the end of the day to relieve fatigue. It has been used as an intoxicant in various parts of the world for centuries and in the United States, for the most part the 20th century. Marijuana was first described in print in a Chinese book of medicine, "Herbal," in the 2nd century B.C., and was used in China as an anesthetic 5,000 years ago. The ancient Assyrians, Persians, Greeks, Romans, and East Indians used the drug to control muscle spasms, reduce pain, and to treat indigestion. It was commonly used in folk medicines in Africa and Asia. As early as 1611, marijuana was cultivated for its fiber in Jamestown, Virginia. In…
Valency can be defined as the combining capacity of an element.The electrons present in the outermostmost shell of an atom are known as valence electrons and they determine the valency.The valence electrons take part in chemical reaction and they determine the chemical properties of the elements.Let us take an example,…
Herbal medicines tend to look primitive and unscientific when compared to synthetic (conventional) drugs, which are thought to be more reliable than those made from plants. Herbal medicine is still the mainstay of about 75-80% of the world population, mainly in the developing countries for primary health care (Kamboj, 2000). This is primarily because of the general belief that herbal drugs are without any side effects, besides being cheap and locally available. The use of plants for healing purposes predates human history and forms the origin of much modern medicine. Many synthetic drugs originated from plant sources: a century ago, most of the few effective drugs were plant-based. Examples include: Aspirin (which is a chemical copy of the analgesic chemical in the bark of willow trees), digoxin (from fox glove), guanine (from the bark of various cinchona tree species which was used in the treatment of malaria) and morphine (from the opium poppy) (Vicker and Zollman, 1999).…