N-methylpiperizine (3.0 mL, 0.03 mol) by continuous stirrer at room temperature until a clear solution was obtained. The benzaldehyde (3.0 mL, 0.03 mol) was added slowly to this mixture with constant stirring. After 48 hours of continuous stirring, a white color precipitate was formed and it was washed with distilled water several times and dried in the air oven at 60 °C. The reaction scheme of MPN is shown in Figure 1.…
Cited: Manrique, C. (2012). Lab 2: Infra-Red (IR)- Nuclear Magnetic Resonance (NMR) Exercises In Molecular Spectroscopy- Structural Determination. Organic Chemistry Lab 2. Dallas. Tx.…
Marilyn Wooten PhD. marilyn.wooten@gmail.com 01T 7:30–11:20 am T/R Ray Still M.S. Raymond.still@gmail.com 02T 6:30 10:20 pm T/R *If you miss a lab you must email me and your lab instructor ASAP. You will have one week to make up the lab and it must be made up in one of the sections listed above. Prerequisites: Completion of or concurrent enrollment in CHE 3643. Course Outline: Simple and multistep synthesis of organic compounds. Text: There is NO text for this lab. Experimental procedures can be found on Blackboard Learn. https://learn.utsa.edu/ Lab notebooks: Instructor's discretion Grades: 60% lab reports 20% Midterm exam 20% Final exam o Exams will be over lab and lecture material. You may use your lab reports during the midterm and final Format of prelab: 1. Title of experiment 2. Abstract A short description of the experiment 3. Include reactions (with mechanism) if applicable. 4. Structures of reactants and products. (only organic compounds) http://www.sigmaaldrich.com Wikipedia also has information on chemical compounds but it is community maintained, so double check the information. 5. Table of physical constants for all chemicals (this includes products) Amount to be used, melting point, boiling point, MW, and density. o http://www.sigmaaldrich.com 6. Hazards of all chemical used in lab. (must be complete or you will be sent out)…
This course will include the major topics of cell biology and microbiology that are foundational for an…
The main goal of this project is to learn how to identify the properties of an unknown ionic compound. In order to do this successfully the group has to use a variety of methods and run several tests on the unknown compound. By doing this the group will be able to identify the different chemical and physical properties of the compound that will help obtain the identity of the specific compound given. The group will devise two syntheses of the compound, and compare them for cost effectiveness, safety and potential yield of the compound.…
2-iodo-6-methoxybenzothiazole synthesized from 2-amino-6-methoxybenzothiazole via a simple and convenient one-pot sequential diazotization–iodination procedure. A quantity of 1.814 g (0.01 mol) of 2-amino-6-methoxybenzothiazole dissolved in 3 ml of water under stirring at 0 °C. To this solution, 3 ml acetic acid and 4.5 ml of the 6 molar sulfuric acid added. Afterward, the reaction mixture stirred for 1 h to obtain a clear solution. Then, a solution of H_2 O (3 ml) containing 0.7g "NaN" O_2 (0.01 mol) added dropwise over 15 min at 0 °C.…
With certain modifications in the reaction procedure, CMPMA was synthesized as reported in literature [11]. Dimethylformamide (DMF) (200 ml) and tri-ethyl amine (TEA) (0.20 mole) were added to a one liter three necked flask equipped with stirrer, thermometer and guard tube and the contents were stirred for 30 minutes. 4-chloro-3-methylphenol (0.20 mole) was added to the reaction mixture. The reaction mixture was heated to 60ºC…
Naphthalimide derivatives are classified under intercalators, having a flat aromatic or heteroaromatic moiety and basic side chains. Amonafide is one of the most widely studied naphthalimides, which binds DNA by intercalation and also as Topoisomerase II inhibitors. The napthalimides showed excellent activity in breast cancer trials but failed in phase III trials due to its side effects and bone marrow toxicity [54]. The justly Naphtalene diimide (NDI) scaffold achieved recently as intercalators and enhance, stabilize, alkylate G-quadruplex are major breakthrough [52]. Restricted analogues of isoCA-4 were designed and a novel series of dihydronaphtalene, tetrahydronaphtalene and naphtalene derivatives were synthesized and cytotoxicity studies…
IR (nujol) 2500-3500 cm-1(-OH), 2922.8 cm-1 and 2853.8 cm-1 (Sp3 C-H); H1NMR (d6-DMSO) 11.487ppm (2, 0), 6.097ppm (M, 2H), 3.160 ppm (D, 2H), 2.995 ppm (S, 2H), 1.280 ppm (S, 2H); 13C NMR (d6-DMSO) 173.979 ppm, 135.199 ppm, 48.714 ppm, 48.269 ppm, 46.384 ppm.…
4. a. Write the appropriate equilibrium expression for each of the following equations. Include the…
Labs reports must be typed and chemical structures must be drawn with ChemDraw. Report must not exceed three pages (including this page). Page limit does not include any attached spectra or references.…
Using the cabon-cabon bond making ability in carbonyl chemistry, Dibenzalacetone is synthesized from 2 equivalent of benzaldehyde and 1 equivalent of acetone in a base catalyzed reaction.…
are always accompanied by vibrational and rotational chang es, and hence a band spectrum is…
Hydrocarbons are organic materials that contain only carbon and hydrogen atoms, these molecules can be saturated or unsaturated and acyclic, cyclic, or aromatic. In this experiment we used a variety of methods to examine the physical and chemical properties of hydrocarbons. The first experiment we tested a variety of solvents to see if they dissolved our alkane (Decalin). One would expect that non-polar solvents will dissolve alkanes because they are non polar as well 1. If the solvent did not dissolve in the alkane we heated the solution with a heat gun, because higher temperature increases solubility because energy in the form of heat can break bonds and allow for the molecules to join together. This is the reversed for a decrease in temperature the molecules move around less so there is less interaction between solute and solvent. We also differentiated alkanes and alkenes. Alkanes only contain c-c single bonds, are saturated, and are the least reactive. Alkenes are c=c double bonds, more reactive than alkanes, and unsaturated. In the next part of the experiment we added bromine to alkenes. This caused an electrophilic halogenation reaction. If the bromine reacted with the alkene the bromine would discolor from orange and turn clear.…
Compound containing imines bases have not only found extensive application in organic synthesis,1-2 but several of these molecules display significant biological activity. In the last decade Schiff base ligands 3-6 have received more attention mainly because of their wide application in the field of catalysis and due to their antimicrobia, 11-12 anti-tuberculosis7 and anti-tumor activity. They easily form stable complexes with most transition metal ion.13-14 The development of the field of…