Preview

SGLT2 Toys: A Cost-Effective Analysis

Good Essays
Open Document
Open Document
305 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
SGLT2 Toys: A Cost-Effective Analysis
According In 2012, 29.1 million people in the United States, approximately 9.3% of the population were diagnosed with diabetes mellitus, of whom 90% to 95% of adults had type 2 diabetes[1]. Although drug costs are increasing, the greatest component of the economic burden of T2DM is the treatment of diabetic complications, which can be reduced with effective management of the disease[2]. The SGLT2 inhibitors are a novel anti-diabetic agents with similar glycemic efficacy to other oral anti-hyperglycemic agents and low risk for hypoglycemia. There is a lack of published literature evaluating the economic benefits of SGLT2 inhibitors such as dapagliflozin. This cost-effectiveness analysis evaluates the long-term economic consequences of SGLT2

You May Also Find These Documents Helpful

  • Good Essays

    "Diabetes - PubMed Health." PubMed Health. Ed. David Zieve and David R. Eltz. U.S. National Library of Medicine, 31 Aug. 2011. Web. 14 Nov. 2011. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002194/>.…

    • 879 Words
    • 4 Pages
    Good Essays
  • Satisfactory Essays

    Scm421merckcasereport 2

    • 790 Words
    • 3 Pages

    Phase Two: If Merck decides to advance into Phase Two there presents a multitude of opportunities. The first decision involves treating just obesity at 10% likelihood. A 10% chance also exists of the drug treating only high cholesterol. There also is a possibility of the drug effectively addressing both conditions at 30%. The chance of the drug not treating any of the maladies is 50%. The cost of completing Phase Two is $40 million. For each condition that is addressed, the decision remains whether to seek out FDA approval. The program suggests if Phase Two is successful, the company has two feasible options, to produce a drug for just obesity or attain a drug that combats both obesity and…

    • 790 Words
    • 3 Pages
    Satisfactory Essays
  • Good Essays

    Bios275 - Week1

    • 522 Words
    • 3 Pages

    Phase III – Performance of drug administered as intended once on market. Compared with other drugs currently on market for same illnesses.…

    • 522 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping and implications for the T2D therapeutics market.…

    • 1008 Words
    • 8 Pages
    Satisfactory Essays
  • Good Essays

    This year, about 580,350 US residents are expected to die of cancer – that’s nearly 1,600 people a day. Cancer is the second most common cause of death in the United States, exceeded only by heart disease. Cancer accounts for nearly 1 out of every 4 deaths in the United States. Drug prices are becoming a developing issue for every disease, especially for people who are uninsured. But the cost of cancer has shown an alarming increase and is steadily growing. As a list of more advanced biotech drugs become available the cost for treatment rounds costing $100,000, or even more, are no longer a rarity. With each new drug means more research which in turn means more money. Patients’ living longer is great news but also means they need treatment for longer periods which also increases cost. Prices reflect manufacturers’ years of research and development investment. Also, many drug companies donate a certain amount of medication to prescription-assistance programs that provide them for free to patients who otherwise couldn’t pay. This is a great program but is also extremely costly and directly contributes to the cost.…

    • 498 Words
    • 2 Pages
    Good Essays
  • Powerful Essays

    Provider Consolidation Paper

    • 3976 Words
    • 16 Pages

    Figure SEQ Figure \* ARABIC 5 Analysis of Price Sensitivities by Disease and Product Characteristics. These can be used to design endpoints in clinical trials…

    • 3976 Words
    • 16 Pages
    Powerful Essays
  • Satisfactory Essays

    Langreth, R. (2014, May). Big pharma 's favorite prescription: higher prices. , (), . Retrieved from…

    • 575 Words
    • 3 Pages
    Satisfactory Essays
  • Powerful Essays

    Challenges in Managing T1D

    • 9001 Words
    • 37 Pages

    As practitioners, the question remains: how do we help patients with type 1 diabetes manage glycaemia while overcoming barriers? In this article, the Global Partnership for Effective Diabetes Management provides practical recommendations to…

    • 9001 Words
    • 37 Pages
    Powerful Essays
  • Satisfactory Essays

    A call to action involving DTCA and regulated profits needs to combine all parties of, manufacturers, patients, providers, government, and public and private health plans. Americans need to become more educated and demand for change from people in higher power positions. Asking your primary care doctor is a great starting place to know what you're paying for. Some may argue that physicians are not reliable enough to speak cost because insurance policies differ, and although this is true doctors should know the difference between generic and new on-the-market medication. Doctors should generally not prescribe medication that their patients cannot afford and try to find alternatives. With many similar drugs, there sure has to be some alternatives…

    • 184 Words
    • 1 Page
    Satisfactory Essays
  • Satisfactory Essays

    Sglt2 Research Paper

    • 92 Words
    • 1 Page

    SGLT2 is a protein in the kidney that facilitates glucose reabsorption. SGLT2 is located in the proximal tubule of the kidneys. It has low-affinity but is a high capacity glucose transporter. It accounts for 90% of glucose reabsorption in kidneys. Inhibition of SGLT2 causes reduced blood glucose due to increased renal glucose excretion. The mechanism of action of this new class of drugs also offers further glucose control by promoting increased activity of insulin, glucose uptake in the muscle cells, decreased gluconeogenesis and improved first phase insulin release from the beta…

    • 92 Words
    • 1 Page
    Satisfactory Essays
  • Best Essays

    Astrazeneca-report

    • 4092 Words
    • 17 Pages

    There will always be a market for new drugs, e.g. Aging population therefore there is a shift in the drugs needed…

    • 4092 Words
    • 17 Pages
    Best Essays
  • Powerful Essays

    Introduction AstraZeneca PLC (AstraZeneca, AZN:NYSE, AZN:LSE) is one of the largest pharmaceutical companies in the world. It was formed in 1999 from the merger of Sweden’s Astra AB and UK’s Zeneca Group plc. Core Activities AstraZeneca is engaged in the discovery, development, manufacturing and marketing of prescription pharmaceuticals and biological products for important areas of healthcare: Cardiovascular, Gastrointestinal, Infection, Neuroscience, Oncology, and Respiratory and Inflammation. One of the key benefits of the merger between Astra and Zeneca is seen as their portfolio of new products in development: AstraZeneca call this their 'product pipeline'. – Cardiovascular product pipeline includes Saxagliptin, Atherosclerosis/dyslipidaemia, Thrombosis and Atrial fibrillation. Gastrointestinal pipeline includes life cycle management initiatives. AstraZeneca's Infection pipeline MedImmune and Dedicated tuberculosis (TB) research. Oncology product pipeline includes Zactima (vandetanib), Zactima (vandetanib), ZD4054 and MedImmune. Dapagliflozin,…

    • 2438 Words
    • 10 Pages
    Powerful Essays
  • Powerful Essays

    Krein, S. L., et al. (2006). "Economics of Diabetes Mellitus." Nursing Clinics of North America…

    • 2529 Words
    • 11 Pages
    Powerful Essays
  • Powerful Essays

    Lifestyle and Diabetes

    • 1705 Words
    • 7 Pages

    Diabetes is a disease that afflicts millions of people worldwide each and every year. For many, diabetes has been with them for their entire lives, others however develop diabetes as they grow older. According to the World Health Organization, (WHO, 2011) 346 million people worldwide have diabetes. Approximately 3.4 million people died from consequences of high blood sugar in 2004 of which more than 80% of diabetes occur in low- and middle-income countries. It was also projected that the number of deaths as a result of diabetes will double between 2005 and 2030. Currently, diabetes imposes a large economic burden on the national healthcare system. Healthcare expenditures on diabetes account for 11.6% of the total healthcare expenditure in the world in 2010.…

    • 1705 Words
    • 7 Pages
    Powerful Essays
  • Best Essays

    Long Term Conditions

    • 2612 Words
    • 11 Pages

    National Institute of Health and Clinical Excellence (NICE) 2009 The Management of Type 2 Diabetes…

    • 2612 Words
    • 11 Pages
    Best Essays