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Research and Review of Articles on Suboxone and Suburex, Agonist and Antagonist Opioid Replacement Drugs.

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Research and Review of Articles on Suboxone and Suburex, Agonist and Antagonist Opioid Replacement Drugs.
Research and review of articles on Suboxone and Suburex, agonist and antagonist opioid replacement drugs.

The purpose of this paper is to explore the pros and cons of Suboxone and Suburex, two treatments for heroin dependence, which are both agonists and antagonists for opioids. The chosen articles, Ling,Walter, et al.’s, “a decade of research by the National Drug Abuse treatment clinical trials network”, Bell, James, et al.’s “a pilot study of bunprenorphine-naxolone combination tablet (Suboxone) in the treatment of opioids dependence” and Mc Cormick’s “management and post-marketing surveillance of CNS drugs”, bring up the benefits and the disadvantages of using Suboxone or Suburex for opioid addictions. Suboxone is the formulation primarily used in the United States for the treatment of opioids addiction. In addition to burponephrine, it contains Naxolone, an opioid antagonist It is an improvement on Suburex, which contains only burponephrine. The naloxone in Suboxone is well absorbed when one takes the medication as directed sublingually. If however, someone dependent on heroin or other strong opioid analgesics administer Suboxone intravenously, the naloxone will precipitate a very intense withdrawal syndrome. Thus, the addition of naloxone decreases the likelihood of the diversion of Suboxone into the drug-using subculture. The prescription medicine is used to treat adults as part of a complete treatment program also including counseling and behavioral therapy. Additionally, physicians prescribe Suboxone in an office setting thus avoiding the stigma of inpatient treatment and helping the patient maintain a normal life style.
Suboxone has become the new replacement drug for opioid users. Reckitt Benckiser Pharmaceuticals UK invented it, the FDA approved it in 2002, and over 7,000 physicians, holding a special license began prescribing it in 2003. Not every health insurance program reimburse Suboxone and

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