Preview

paper critique

Powerful Essays
Open Document
Open Document
2483 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
paper critique
Research Paper Critique
Overcoming Biological Barriers 2013-2014

Abstract
Is the abstract a concise summary?

Does it focus on results and conclusions?
The abstract of this paper is concise. The aim of this study was made clear. It was clear from the abstract that the aim of this paper was to develop chitosan microspheres of verapamil to administer it intranasally in order to enhance its low bioavailability.

It was an interesting fact that the abstract started by talking about chitosan microspheres and their use. This makes it easier for the reader to understand the title and what the study is actually developing. The abstract mentioned how the study was done. All the parameters investigated in this study were mentioned in a concise way in the abstract again giving the reader an overview of the paper. One could argue that thorough detail was included regarding the method; nonetheless this was done in an appropriate and concise way. It was clear that two methods were used in order to prepare the chitosan microspheres.

The author did focus on the results and conclusion. It was clear to the reader that the chitosan microspheres prepared had particle size suitable for nasal deposition and that the spray drying technique was superior to the precipitation technique in achieving higher entrapment efficiency of the drug. It is also clear that bioavailability studies demonstrated that nasal microspheres exhibited higher bioavailability when compared to nasal solution of verapamil.

Morphological studies were done, however this was not mentioned in the abstract. This could be due to the fact that the author did not want to include too much information in the abstract.
The abstract is ended with a concluding sentence which summarizes nicely the results/ conclusion of this study.
To a good extent the abstract of the study was representative of the article. Who reads it can understand the overall purpose and method

You May Also Find These Documents Helpful

  • Satisfactory Essays

    Mucoadhesive properties prolong the retention time of the bead’s dose in the targeted site the colon [23], [50]. Since the dose is intended to colonic release, mucoadhesion parameters play a key role in the efficiency of the form. The beads remain longer in contact with colonic mucosa when they have more mucoadhesive property. As a result the probiotics will have enough time to get released from beads and colonize the colon [37], [51]. It is therefore judicious to consider formulas with high mucoadhesion to colonic tissues, to have prolonged duration of action and enhanced efficiency which help in reducing the dosing frequency. Figure 3 shows the mucoadhesiveness properties of different types of beads on jejunal [A] and colonic mucosa [B]. Generally the mucoadhesion strength decreases with time, regardless of the mucosal type or bead type. In the case of jejunal mucosa [A] no significant differences were observed between…

    • 405 Words
    • 2 Pages
    Satisfactory Essays
  • Satisfactory Essays

    A major hurdle that has prevented the commercialization of many promising poorly soluble drug candidates is dissolution rate-limited bioavailability or permeation rate-limited bioavailability. Buccal route of administration provides better penetration of therapeutic and diagnostic agents, and a reduced risk in comparison to conventional treatments. This leads to greater therapeutic efficacy, provides a more comfortable administration for the patient and allows preventing over dose.…

    • 305 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Fruit Fly Lab Report

    • 1286 Words
    • 6 Pages

    2. Each vial was prepared with a culture containing food prepared by adding 1 scoop of food, and equal amount of water, and a pinch of yeast and allowed to sit for several minutes.…

    • 1286 Words
    • 6 Pages
    Good Essays
  • Good Essays

    Methodology: Using auto-pipette (20-100 microlitre), pipetted 0.06 mg of Taxifolin was added to 10ml conical flask and made up to the mark (10ml) with H2O.This procedure was repeated with the same amounts foe silymarin stock solution and silybum marianum extract. Taxifolin was transferred to 2ml brown bottle for HPLC auto sampler, this was also done to silymarin stock solution. Silybum marianum extract was filtered via a syringe filter (0.2 microlitre).The three samples were tested for concentrations of taxifolin via HPLC.This process was repeated a further 20 times with different amounts of taxifolin, silymarin stock solution and silybum marianum extract. Results of Taxifolin standard shown in table 1 and figure 1.…

    • 818 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    The purpose of the sections of a research article should start with a title, author, and contact information. The Abstract is next; this is a summary of the article. The summary provides an general idea of the article, which is helpful to establish if the article is significant to the reader’s investigation. An abstract will usually follow a regular format like APA or something that is similar. The author or authors in brief state why the research article is significant, the methodology, results, and concluding proclamation regarding the results.…

    • 1224 Words
    • 5 Pages
    Powerful Essays
  • Powerful Essays

    kevin

    • 8848 Words
    • 29 Pages

    Pharmaceuticals play a very important role in the health and wellbeing of mankind. It is the study that concerns the design, action, delivery, disposition, physical and chemical engineering by the form of drugs (University of California, n.d.). The desperate need for drugs to attempt to restore one’s health…

    • 8848 Words
    • 29 Pages
    Powerful Essays
  • Better Essays

    To began with the article critique, Parahoo (2006) states that an abstract should briefly states the study aim, design, methods, sampling and main funding. Looking at both articles these are apparent.…

    • 2843 Words
    • 12 Pages
    Better Essays
  • Satisfactory Essays

    Critique Paper 1

    • 349 Words
    • 2 Pages

    I chose to write about Hung Liu, Mu Nu (Mother and Daughter). The painting by Hung Lui in 1997; Liu used oil on canvas as her medium. The result is a timeless 80 x 140 inch by inch painting that is currently housed in Kemper Museum of Contemporary Art, Museum. The roughly 7 by 11 foot painting shows two women hunched over, ropes tied around their waist, strain on hands and knees to pull a heavy load. The point of this searing image, which calls to mind slavery and extreme poverty, is that they’re performing the labor of oxen or machines. The lack of shoes, tools, and simple cloths reinforce the depiction of poverty. The negative space is filled with a large, ghostly looking, shallow body of water and a crowd of earthy colored rocks.…

    • 349 Words
    • 2 Pages
    Satisfactory Essays
  • Satisfactory Essays

    Bead Mill Yeast

    • 212 Words
    • 1 Page

    The size of the beads is vital. Optimal size for bacteria and spores is 0.1, while yeast, mycelia, microalgae, and unicellular animal cells, such as leucocytes or trypsin zed tissue culture cells is 0.5 mm and 1.0 or 2.5 mm for tissues. Speed of disruption is increased about 50% by using zirconia silica or zirconia rather…

    • 212 Words
    • 1 Page
    Satisfactory Essays
  • Good Essays

    Women of Color

    • 850 Words
    • 4 Pages

    The article was introduced with an abstract, which provided the stance or thesis developed by the article as well as a brief overview of main points. The rationales for the article and for the research it describes were also included. The paragraphs in the body were short and therefore the information in each paragraph was easy to access, however there were only 3 body headings, which meant that there was a lot of quite detailed information contained under each heading. As the article described a research study that was conducted by the author, the article contained the conventional information normally provided in such a study. For example there are sections related to the background and significance of the research, a review of the literature and the methodology as well as the data collection and analysis techniques used. The findings and conclusions were developed towards the end of the article however the conclusion was very short, lacking a comprehensive summary of the main points covered by the article. However the short conclusion did develop future policy and research directions. References were cited in-text and set out clearly in the literature cited…

    • 850 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Critical Appraisal Paper

    • 1796 Words
    • 8 Pages

    (2) Yes, the abstract succinctly describes the purpose of the clinical investigation posed in the paper, the patients and methods used for the investigation, the results, and the conclusions. Yes, the purpose, patients and methods, results, and conclusions, provided in the abstract, are with adequate details. The purpose briefly mentions what is the subject of the investigation and why it has done; the patients and methods concisely informs who were the patients and what methods were used; the results summarizes the most important results obtained; the conclusions succinctly notes what the results mean and how these outcomes can…

    • 1796 Words
    • 8 Pages
    Good Essays
  • Better Essays

    The purpose of the study was clearly identified in the title of the article. The article maintained logical consistency and…

    • 1169 Words
    • 5 Pages
    Better Essays
  • Good Essays

    Biology Review Paper

    • 1423 Words
    • 6 Pages

    A review is a comprehensive synthesis of results from a wide and complex set of studies…

    • 1423 Words
    • 6 Pages
    Good Essays
  • Good Essays

    Mycophenolate Case Study

    • 839 Words
    • 4 Pages

    The cellcept® IV solution was characterized by invitro in order to determine the benefits of the suspension of Mycophenolate mofetil over its solution form. The results have shown that aerosolization performance of both formulations were excellent. 24 hour single dose, pharmacokinetic studies followed by the inhalation both formulations and oral cellcept® administration were performed in rats. Mycophenolate mofetil was rapidly and completely metabolized into the active metabolite by oral drug administration where as partial and slow metabolism was observed by pulmonary drug administration. Hence the results have shown that inhaled Mycophenolate mofetil suspension form was displayed well favourable pharmacokinetic data than that of inhaled cellcept® IV solution…

    • 839 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Molisch Test Lab Report

    • 419 Words
    • 2 Pages

    In this experiment, all the test solutions show a positive test with Molisch reagent and concentrated sulfuric acid to form a violet ring at the interface of two layers. This is because the samples used in this experiment are maltose, glucose and starch which are considered as carbohydrate that should give a positive reaction. Monosaccharides give a rapid positive test compare to disaccharides and polysaccharides which will react slower. Therefore, the…

    • 419 Words
    • 2 Pages
    Good Essays