Mouse Model Of Respiration
In this mouse model (Fig 1 A-C), brief periods of gasping and shallow respirations, a decrease in breathing rate or transient termination of breathing before resuming a normal respiration define as loss of consciousness (unconscious). Our results indicated that an impact caused a short-term unconsciounsness (7.5±4.7, 7.8±5.5, 10.2±8.8, 9.5±8.0 sec at each impact separately) (Fig 1D). During the impactions, no mouse showed skull fractures, subarachnoid, epidural or subdural hemorrhage. H&E staining of the brain sections were histologically normal and showed no remarkable tissue disorganization, or subdural or interstitial hemorrhage in the cortex, hippocampus, cerebellum and brain stem (Fig 2A). Astrocytic activation and proliferation is thought