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Microscopic Anatomy Of Muscle Essay

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Microscopic Anatomy Of Muscle Essay
Muscle Study Guide

Microscopic Anatomy Of A Muscle:
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Big(-); Muscle, fascicle, muscle fiber, myofibril, myofilaments; Small(+)

Endomysium: Thin connective tissue investing each muscle cell.
Epimysium: Connective tissue ensheathing the entire muscle.
Fascicle: A discrete bundle of muscle cells.
Fiber: A muscle cell.
Myofilament: Actin- or myosin- containing structure.
Perimysium: Connective tissue surrounding a fascicle.
Sarcolemma: Plasma membrane of the muscle cell.
Sarcomere: Contractile unit of a muscle.
Tendon: Cordlike extension of connective tissue beyond the muscle, serving to attach it to the bone.
7 Golden Rules Of Muscle Activity: 1. Get smaller as they contract. 2. Cross at least one joint. 3. Bulk of the muscle
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The rise of intracellular Ca2+ triggers synaptic vesicles filled with acetylcholine (ACh) to pass readily through pre-synaptic membrane into the synaptic cleft. 6. The ACh vesicles travel across the synaptic cleft, which is only 50 nm wide. The bind to acetylcholine receptors, namely nicotinic acetylcholine receptors (nAChR), the nAChR are found within the sacrolemma, which is the outer surface of a muscle cells. 7. An new action potential is then generated and depolarizes the transverse tubules (t-tubules), which lie along the sacrolemma 8. A depolarization of the T-Tubule causes Ca2+ release from the sarcoplasmic reticulum (SR) 9. Ca2+ binds to the tropnon-tropomysion complex in the actin filaments. This releases the inhibition that prevented actin from combining with myosin 10. During muscle action, actin combines with myosin-ATP. Action also activates the enzyme myosin ATP-ase, which then splits ATP. The energy from this reaction produces myosin cross bridge movement and creates tension. 11. ATP binds to the myosin cross bridge; this breaks the actin-myosin bond and allows the cross bridge to dissociate from actin. The filaments then slide past each other and the muscle

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