Methylaminolevulinate and Red-Light Photodynamic Therapy in Patients with Facial Photodamage
Methylaminolevulinate And Red-Light Photodynamic Therapy In Patients With Facial Photodamage
I chose this article because I am interested in dermatology and hope to become a PA in dermatology. This article is very straightforward and it is easy to understand the experiment. The article is related to the integumentary system.
Science is always searching for new and innovative ways to prevent aging. Currently laser technology offers many skin rejuvenating therapies that are beneficial but also have many drawbacks. Photodynamic therapy (PDT) efficacy has been demonstrated for the treatment of superficial basal cell cancers, Bowen’s disease and actinic keratoses (H.-I. Garcia). Good cosmetic reults in these treatments with PDT has led to expansion of use of PDT in photoageing. Recently studies have been performed to see if treatment with methyl-aminolevulinate and red light therapy could reduce facial photodamage (H.-I. Garcia).
The study assess the efficacy of methyl aminolevulinate and red-light treatment on facial photodamage. The hypothesis was to see if the total facial photodamage global score decreases 1 grade compared to the baseline after use of MAL and red-light compared to placebo and red-light (H.-I. Garcia). The subjects in the study were required to have a symmetrical photodamage grade of 2 or 3 according to Dover’s modified global photodamage scale. Subjects ranged from 35-75 years of age and subjects excluded were those who were pregnant or nursing, had an active infectious skin disorder, photosensitizing disorder, or were using drugs that induced photosensitivity (H.-I. Garcia).
The subjects were administered two split face treatments 2-3 weeks apart with red-light and methyl-aminolevulinate on one side of the face and red light and a placebo on the other. The primary assessment of photodamage over the entire face was assessed 1 month after the second treatment. A secondary assessment was also performed for fine lines, mottled
I chose this article because I am interested in dermatology and hope to become a PA in dermatology. This article is very straightforward and it is easy to understand the experiment. The article is related to the integumentary system.
Science is always searching for new and innovative ways to prevent aging. Currently laser technology offers many skin rejuvenating therapies that are beneficial but also have many drawbacks. Photodynamic therapy (PDT) efficacy has been demonstrated for the treatment of superficial basal cell cancers, Bowen’s disease and actinic keratoses (H.-I. Garcia). Good cosmetic reults in these treatments with PDT has led to expansion of use of PDT in photoageing. Recently studies have been performed to see if treatment with methyl-aminolevulinate and red light therapy could reduce facial photodamage (H.-I. Garcia).
The study assess the efficacy of methyl aminolevulinate and red-light treatment on facial photodamage. The hypothesis was to see if the total facial photodamage global score decreases 1 grade compared to the baseline after use of MAL and red-light compared to placebo and red-light (H.-I. Garcia). The subjects in the study were required to have a symmetrical photodamage grade of 2 or 3 according to Dover’s modified global photodamage scale. Subjects ranged from 35-75 years of age and subjects excluded were those who were pregnant or nursing, had an active infectious skin disorder, photosensitizing disorder, or were using drugs that induced photosensitivity (H.-I. Garcia).
The subjects were administered two split face treatments 2-3 weeks apart with red-light and methyl-aminolevulinate on one side of the face and red light and a placebo on the other. The primary assessment of photodamage over the entire face was assessed 1 month after the second treatment. A secondary assessment was also performed for fine lines, mottled
Cited: H.-I. Garcia, et al. ""A Prospective Split-Face Double-Blind Randomized Placebo-Controlled Trial To Assess The Efficacy Of Methyl Aminolevulinate + Red-Light In Patients With Facial Photodamage."." Journal Of The European Academy Of Dermatology & Venereology 25.1 (2011): 45-98.