On the basis of the material available both in the scientific literature and on the web, this paper aims to provide a pharmacological, chemical and behavioural overview of the novel compound methoxetamine. This is a dissociative drug related to ketamine, with a much longer duration of action and intensity of effects. A critical discussion of the availability of information on the web of methoxetamine as a new recreational trend is here provided. Those methodological limitations, which are intrinsically associated with the analysis of online, non-peer reviewed, material, are here discussed as well. It is concluded that the online availability of …show more content…
The desired effects may vary according to the dosage and the modality of intake, these include euphoria, empathy, ‘cosiness’, pleasant intensification of sensory experiences especially whilst listening to music, mild-to-strong sense of dissociation from the physical body, distortion of the sense of reality, vivid hallucinations, introspection and brief antidepressant effects (Bluelight 2010; Erowid 2010; Psychonaut
2010; Purechemicals 2010; Bluelight 2011; DrugsForum 2011; Erowid 2011; Hipforums 2011). Some users’ comments on their MXE experience included
‘music sounds great’, ‘trapped inside a glass chopping board’, ‘not for social situation’, ‘feeling like another inanimate object’ and ‘. . .just seems so absurdly surreal and it makes no sense, but I’m quite happy just to stare at the TV screen, feeling all snugly and warm’.
Somebody described MXE as a ‘big Christmas cardigan’, whose intake was providing both ‘spinning sensations’ and ‘naturalistic hallucinations in waves’, overall referring to the ‘M-Hole’, as opposed to the ketamine ‘K-hole’ (Erowid 2011). The term is typically referring to a subjective state of dissociation
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