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Informative Speech Outline
Topic: Multiple Sclerosis

I. Introduction
a. Attention Device:
i. How many of you know somebody living with multiple sclerosis (MS)? ii. According to the National MS Society, it's estimated that some 400,000 Americans have MS, with women developing the disease at twice the rate of men.
b. Thesis:
i. Multiple sclerosis is a very devastating and debilitating disease. MS is important to me because my mother was diagnosed with MS the summer of 2009. I’ve witnessed the long-term effects of this disease firsthand.
c. Forecast of Main points: Today I will be discussing…
i. What is multiple sclerosis? ii. What causes multiple sclerosis? iii. What are the symptoms of ms? iv. Is there treatment for ms?
Transition: I know some of you may be wondering what MS is, and why you should care. Let’s begin with what MS is.
II. Body
a. Point #1 – What is multiple sclerosis?
i. According to IU Health, multiple sclerosis (MS) is a chronic disease of the central nervous system. Myelin is a fatty tissue that surrounds and protects the nerve fibers. The immune system attacks the myelin sheath resulting in scar tissue called sclerosis. These areas are also called plaques or lesions. When damaged in this way, the nerves are unable to conduct electrical impulses to and from the brain. ii. It is an unpredictable condition that can be relatively benign, disabling, or devastating. Some individuals with MS may be mildly affected, while others may lose their ability to see clearly, write, speak, or walk when communication between the brain and other parts of the body becomes disrupted.
b. Point #2 – What causes multiple sclerosis?
i. According to the Multiple Sclerosis Foundation, the exact cause of MS remains currently unknown, but researchers believe that a combination of several factors may be involved. Studies are ongoing in the following areas:
1. Immunological reaction
2. Viral or Other Infectious Agents
3. Environmental Factors
4. Genetic Factors
c. Point #3 – What are the symptoms

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