Gadolinium
Gadolinium is a paramagnetic metal icon. These paramagnetic icons move differently within a magnetic field in which these make the gadolinium useful for something more familiar in today’s medicine such as MRI. Gadolinium helped doctors and medical professionals to be able to see a patient’s internal organs, inflammation, tumors, blood vessels, and tissue. The quality of MRI’s are enhanced by altering the magnetic properties of water molecules when gadolinium is used. Gadolinium used by itself is toxic, but when it is used in contrast agents it bonds with a molecule called a chelating agent. This controls the distribution throughout the body. The chelating agent controls the toxicity of the contrast and helps maintain the magnetic properties.
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It is similar to scleroderma and scleromyxedema but on distinct difference, NSF is caused by the exposure to gadolinium when patients with renal insufficiently are given gadolinium contrast for a MRI. Patients with NSF most likely develop large patches on the indurated skin with fibrotic nodules and plaques. Some patients develop flexion contractures with accompanying limitation of range of motion. NSF resembles scleromxedema in that it manifests with a proliferation of dermal fibroblasts and dendritic cells, thickened collagen bundles, increased elastic fibers and mucin deposition. This disease is not more common in people with a particular race sex or age. NSF has been reported equally among all age groups and ethnic …show more content…
Gadolinium based contrast agents studies revealed they were linked to brain hypersensitivity in two areas, the dentate nucleus and globus pallidus, which correlated with the number of gadolinium exams. At the present time it is not known what the higher level of hypersensitivity mean but hyper-intensity in the dentate nucleus is associated with people who have multiple sclerosis. Patients with multiple sclerosis have a higher number of enhanced MRI scans. Hyper-intensity of the globus pallidus is linked with liver
It is similar to scleroderma and scleromyxedema but on distinct difference, NSF is caused by the exposure to gadolinium when patients with renal insufficiently are given gadolinium contrast for a MRI. Patients with NSF most likely develop large patches on the indurated skin with fibrotic nodules and plaques. Some patients develop flexion contractures with accompanying limitation of range of motion. NSF resembles scleromxedema in that it manifests with a proliferation of dermal fibroblasts and dendritic cells, thickened collagen bundles, increased elastic fibers and mucin deposition. This disease is not more common in people with a particular race sex or age. NSF has been reported equally among all age groups and ethnic …show more content…
Gadolinium based contrast agents studies revealed they were linked to brain hypersensitivity in two areas, the dentate nucleus and globus pallidus, which correlated with the number of gadolinium exams. At the present time it is not known what the higher level of hypersensitivity mean but hyper-intensity in the dentate nucleus is associated with people who have multiple sclerosis. Patients with multiple sclerosis have a higher number of enhanced MRI scans. Hyper-intensity of the globus pallidus is linked with liver