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Exercise 2 Histology Review Supplement and Question to Histology Review Supplement Questions

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Exercise 2 Histology Review Supplement and Question to Histology Review Supplement Questions
Kathleen thomason October 2, 2012

Skeletal Muscle physiology exercise

Electrical Stimulation

name each phase of a typical muscle twitch and on the following line. Describe what is happening in each phase. a) latent- is a short period between the time of stimulation and the beginning of contraction b). Contraction – at this stage the muscle reaches its peak in contraction. Relaxation -Muscle is shortened, returns to zero and back initial length.

In activity 2 how long was the latent period? It was 2.2 msec. Describe the chemical changes that are occurring during this period. Calcium levels are low since muscle contraction is not at its peak. Preparing on the contraction Ca begin the process of sending Acetylcholine binding to sarcoplasm.

The Graded Muscle Response to Increased Stimulus Intensity

From activity 3, describe the effect of increasing the voltage. What happened to the force generated and why did this change occur? Higher voltage results in higher force and a higher contractile force. How does this change occur in vivo? T the more stimulus of muscle require more work on the cells which required more Ca2t to facilitate this stimulus increase. In activity 4, you looked at the effect of stimulating the muscle times in a short period with complete relaxation between the stimuli. Describe the force of contraction with each subsequent stimulus. Answer: The force of contraction is higher with each subsequent stimulus.

Describe the chemical changes that are thought to correlate to this change in vivo. Answer: This requires more Ca t2 in the sarcoplasm and more activity on the thin filament for cross-bridge attachments.

In activity 5, what was the effect of increasing the frequency of stimulation. Answer: Increase frequency of stimuli result in increased muscle tension Compare and contrast wave summation with recruitment ( multiple

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