Testing is performed for LC50 by calculating the concentration of ethylene glycol over a specific time until a 50% death rate is reached.( OSH Answers Fact Sheets) Goldfish (Carassius auratus) LC50 equals >5,000,000 ug/L concentration for 24 hours. Rainbow trout (Oncorhynchus mykiss) LC50 equals >20000000 ug/L concentration for 96 hours. Atlantic salmon (Salmo salar) LC50 equals >1000000 ug/L concentration for 24 hours. LD50 is determined by given a known amount of ethylene glycol to test animals that cause the death of 50% of the test subjects. (OSH Answers Fact Sheets) A mouse (Mus) LD50 for oral consumption equals 5,500 mg/kg. Rat (Rattus) LD50 for oral consumption equals 4,700 mg/kg. Rabbit (Oryctolagus cuniculus) LD50 for applied to the skin equals 9,530 uL/kg. (Material Safety Data Sheet Ethylene Glycol) There have been several studies done with animal trying to determine if ethylene glycol is a carcinogen, but none of the studies have produced any association between the two. It is determine thought that since ethylene glycol is teratogenic to humans since studies on mice and rats have shown results of skeletal dysplasia, neural tube closure and craniofacial effects. (Medical Management Guidelines for Ethylene Glycol) There have been no links showing that ethylene glycol is a
Testing is performed for LC50 by calculating the concentration of ethylene glycol over a specific time until a 50% death rate is reached.( OSH Answers Fact Sheets) Goldfish (Carassius auratus) LC50 equals >5,000,000 ug/L concentration for 24 hours. Rainbow trout (Oncorhynchus mykiss) LC50 equals >20000000 ug/L concentration for 96 hours. Atlantic salmon (Salmo salar) LC50 equals >1000000 ug/L concentration for 24 hours. LD50 is determined by given a known amount of ethylene glycol to test animals that cause the death of 50% of the test subjects. (OSH Answers Fact Sheets) A mouse (Mus) LD50 for oral consumption equals 5,500 mg/kg. Rat (Rattus) LD50 for oral consumption equals 4,700 mg/kg. Rabbit (Oryctolagus cuniculus) LD50 for applied to the skin equals 9,530 uL/kg. (Material Safety Data Sheet Ethylene Glycol) There have been several studies done with animal trying to determine if ethylene glycol is a carcinogen, but none of the studies have produced any association between the two. It is determine thought that since ethylene glycol is teratogenic to humans since studies on mice and rats have shown results of skeletal dysplasia, neural tube closure and craniofacial effects. (Medical Management Guidelines for Ethylene Glycol) There have been no links showing that ethylene glycol is a