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Ebstein's Anomaly Research Paper

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Ebstein's Anomaly Research Paper
Cody Notbohm
Dr. Lori Wilson
BIO 460
24 November 2015
Ebstein’s Anomaly: An Overview Ebstein’s anomaly is a congenital malformation within the heart defined by clear apical displacement of the septal and posterior leaflets of the tricuspid valve. This condition can lead to right ventricular atrialization, which, in other words, a portion of the right ventricle functionally becomes a part of the right atrium due to abnormal positioning of the leaflets or flaps. Moreover, the atrialization of the right ventricle leads to a larger than normal right atrium and a smaller than normal right ventricle in size. With Ebstein’s anomaly, pulmonary atresia, right ventricular conduction deficiencies, atrial septal defect, and Wolff-Parkinson-White syndrome are common comorbidities that accompany this congenital malformation (Cite).
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The right ventricular atrialization effect is what causes blood flow to be stagnant within the right atrium, because during ventricular systole the atrialized portion of the right ventricle contracts in sync with the entire right ventricle, inflicting a backward flow of blood into the right atrium. With regards to pressures, “Right ventricular and pulmonary artery pressures are usually normal in patients with the anomaly, although the right ventricular end-diastolic pressure may be increased” (Cite). Also, atrial septal defect can occur, which lowers oxygen levels throughout the body and results in deoxygenated blood in the right atrium to venture into the left atrium

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