Drugs
1. Which dosage forms are most appropriate for administering drugs to pediatric patients? Adults?
The dosage forms that are the most appropriate for administering drugs to pediatric patients is chewable tablets which makes it much easier than trying to have the children swallow a pill and as well oral disintegrating capsules, suspensions or solution/syrups. For adults it is different because they can receive the drugs just about anyway as long as there is not any life threatening injuries obstructing the route. 2. What are the processes involved in disintegration and dissolution?
Disintegration is actually very closely related to dissolution. It is the process where the oral dosage form falls apart or 'disintegrates' into smaller aggregates once placed into ones mouth. And Disintegration typically takes the particles down to 2mm diameter in size once it breaks apart. The process of dissolution is When a substance dissolves, it may separate into ions or it may remain in molecular form If it completely separates into ions so that practically none of the molecular form remains.
3. Give a definition of pharmacokinetics.
Pharmacokinetics is the study of the action of drugs within the body, which can, in many respects, be envisioned more accurately as the actions of the body on an administered drug. It includes studies of the mechanisms of drug absorption, distribution, metabolism, and excretion; onset of action; duration of effect; biotransformation; and effects and routes of excretion of the metabolites of the drug
4. Examine the processes of absorption, distribution, metabolism, and excretion, and explain why they occur in this order.
The reason why absorption, distribution, metabolism and excretion happen in that exact order is because absorption is the first step in the process in which it may occur through the alimentary tract, skin, lungs, via the eye, mammary gland, or uterus, as well as from sites of injection. Then next is distribution
The dosage forms that are the most appropriate for administering drugs to pediatric patients is chewable tablets which makes it much easier than trying to have the children swallow a pill and as well oral disintegrating capsules, suspensions or solution/syrups. For adults it is different because they can receive the drugs just about anyway as long as there is not any life threatening injuries obstructing the route. 2. What are the processes involved in disintegration and dissolution?
Disintegration is actually very closely related to dissolution. It is the process where the oral dosage form falls apart or 'disintegrates' into smaller aggregates once placed into ones mouth. And Disintegration typically takes the particles down to 2mm diameter in size once it breaks apart. The process of dissolution is When a substance dissolves, it may separate into ions or it may remain in molecular form If it completely separates into ions so that practically none of the molecular form remains.
3. Give a definition of pharmacokinetics.
Pharmacokinetics is the study of the action of drugs within the body, which can, in many respects, be envisioned more accurately as the actions of the body on an administered drug. It includes studies of the mechanisms of drug absorption, distribution, metabolism, and excretion; onset of action; duration of effect; biotransformation; and effects and routes of excretion of the metabolites of the drug
4. Examine the processes of absorption, distribution, metabolism, and excretion, and explain why they occur in this order.
The reason why absorption, distribution, metabolism and excretion happen in that exact order is because absorption is the first step in the process in which it may occur through the alimentary tract, skin, lungs, via the eye, mammary gland, or uterus, as well as from sites of injection. Then next is distribution