Generic & Brand Names Dose, Strength & Formulation Indication/Mechanisms of Drug Action Adverse/ Side Effects Drug Interaction Nursing Responsibilities Rationale Client Teaching
Generic:
Ferrous Sulfate
Brand:
Sorbifer
Classification: Antianemic Ordered:
Give FeSO4 (Sorbifer) durule OD
Timing:
OD
Duration:
Other Forms:
Drops: 75 mg/0.6ml
Elixir: 220 mg/5ml
Tablets: 195 mg, 300 mg, 325 mg, 187 mg, 200 mg
Tablets (extended-release): 160 mg Indications:
• Treatment for:
Iron deficient anemia
Decreased absorption of Iron
Long term bleeding
Malnutrition
Prophylaxis of anemia
Prophylaxis of miscarriage and early birth
Mechanism of Action:
Chemical effect: Provides elemental iron, an essential component in formation hemoglobin.
Therapeutic effect: Relieves iron deficiency.
Adverse Reaction:
GI: anorexia, black stools, constipation, diarrhea, epigastric pain, nausea, vomiting.
Other: temporary staining of teeth (drops, suspension).
Interactions:
Drug-drug: Antacids, cholestryramine resin, leveodopa, tetracycline, vitamin E: May decrease iron absorption. Separate doses by 2 to 4 hours.
Vitamin C: May increase iron absorption. Suggest patient take vitamin C with drug.
Drug-food: Cereals, cheese, coffee, eggs, milk, tea, whole-grain breads, yogurt: May impair iron absorption. Advise against use together. Assessment:
Obtain baseline assessment of patient’s iron deficiency before starting therapy.
Evaluate hemoglobin level, hematocrit, and reticulocyte count during therapy.
Asses patient’s and family’s knowledge of drug therapy.
Implementation:
Give tablets with juice or water, but not with milk or antacids.
Dilute liquid forms in juice or water, but not with milk or antacids.
Don’t crush or allow patient to chew extended-release forms.
Be alert for adverse