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Drug Study
DRUG STUDY

Generic & Brand Names Dose, Strength & Formulation Indication/Mechanisms of Drug Action Adverse/ Side Effects Drug Interaction Nursing Responsibilities Rationale Client Teaching
Generic:

Ferrous Sulfate

Brand:

Sorbifer

Classification: Antianemic Ordered:

Give FeSO4 (Sorbifer) durule OD

Timing:

OD

Duration:

Other Forms:

Drops: 75 mg/0.6ml
Elixir: 220 mg/5ml
Tablets: 195 mg, 300 mg, 325 mg, 187 mg, 200 mg
Tablets (extended-release): 160 mg Indications:

• Treatment for:
Iron deficient anemia
 Decreased absorption of Iron
 Long term bleeding
 Malnutrition
 Prophylaxis of anemia
 Prophylaxis of miscarriage and early birth

Mechanism of Action:

Chemical effect: Provides elemental iron, an essential component in formation hemoglobin.
Therapeutic effect: Relieves iron deficiency.

Adverse Reaction:

GI: anorexia, black stools, constipation, diarrhea, epigastric pain, nausea, vomiting.
Other: temporary staining of teeth (drops, suspension).

Interactions:

Drug-drug: Antacids, cholestryramine resin, leveodopa, tetracycline, vitamin E: May decrease iron absorption. Separate doses by 2 to 4 hours.
Vitamin C: May increase iron absorption. Suggest patient take vitamin C with drug.
Drug-food: Cereals, cheese, coffee, eggs, milk, tea, whole-grain breads, yogurt: May impair iron absorption. Advise against use together. Assessment:

 Obtain baseline assessment of patient’s iron deficiency before starting therapy.
 Evaluate hemoglobin level, hematocrit, and reticulocyte count during therapy.
 Asses patient’s and family’s knowledge of drug therapy.

Implementation:

 Give tablets with juice or water, but not with milk or antacids.
 Dilute liquid forms in juice or water, but not with milk or antacids.
 Don’t crush or allow patient to chew extended-release forms.
 Be alert for adverse

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