Aspirin And Oil Of Wintergreen Lab Report
Experiment 22: Synthesis of Aspirin and Oil of Wintergreen
Performed 01/31/2013
Received 02/07/2013
Organic molecules have a wide range of applications occur both intracellular as well as in many different industries. The reactions use the reactivity of functional groups attached to organic molecules, as well as general chemistry concepts such as Le Chatelier’s Principle (). The synthesis of Aspirin (its chemical name being acetylsalicylic acid) and of oil of wintergreen (with its chemical name as methyl salicylate) both occur by addition of an ester to the molecules. Both syntheses have salicylic acid on the reactants side, however differ in the second reactant that ‘esterifies’ the salicylic acid. This is a vital process in the …show more content…
In the formation of acetylsalicylic acid (Aspirin), salicylic acid and acetic anhydride were made to react in the presence of an acid catalyst, namely sulfuric acid. In the formation of methyl salicylate (oil of wintergreen), salicylic acid and methanol were reacted together in the presence of the same acid catalyst, sulfuric acid. The designation of Part 1 for this experiment was used for the synthesis of Aspirin. To prepare the heating mechanism for the experiment, 250mL of tap water was poured into a 400mL beaker, and this water was then heated on a hot plate to 85⁰C. As the water was heating, the mixture to be heated was concocted. First, 2.595g of salicylic acid was weighed by first tarring a plastic weigh boat on a scale, and then adding the salicylic acid powder-like solid. This amount was then poured into a 125mL Erlenmeyer flask. Next, 5mL of acetic anhydride was measured using a 10mL graduated cylinder, which was then added to the same Erlenmeyer flask. Lastly, 5 drops of the concentrated sulfuric acid catalyst were added to the Erlenmeyer flask, and this was mixed for 5 seconds using a swirling …show more content…
First, 2 medium-sized test tubes were obtained from the front of the laboratory, cleaned using the basic soap and water, and dried. A pea-sized portion of the product was added to the first test tube, using a clean scapula. The same sized amount of salicylic acid added to the other test tube using a separate clean scapula. Each test tube was then labeled with the contents it contained. 5mL of iron (III) chloride (FeCl3) was then measured in two separate clean graduated cylinders (5mL in each cylinder) and 5mL was added to each test tube. Following the addition, a lighter magenta color resulted in the test tube with the experimental product yield, when compared to the tube containing the salicylic acid, which turned a darker shade of
Performed 01/31/2013
Received 02/07/2013
Organic molecules have a wide range of applications occur both intracellular as well as in many different industries. The reactions use the reactivity of functional groups attached to organic molecules, as well as general chemistry concepts such as Le Chatelier’s Principle (). The synthesis of Aspirin (its chemical name being acetylsalicylic acid) and of oil of wintergreen (with its chemical name as methyl salicylate) both occur by addition of an ester to the molecules. Both syntheses have salicylic acid on the reactants side, however differ in the second reactant that ‘esterifies’ the salicylic acid. This is a vital process in the …show more content…
In the formation of acetylsalicylic acid (Aspirin), salicylic acid and acetic anhydride were made to react in the presence of an acid catalyst, namely sulfuric acid. In the formation of methyl salicylate (oil of wintergreen), salicylic acid and methanol were reacted together in the presence of the same acid catalyst, sulfuric acid. The designation of Part 1 for this experiment was used for the synthesis of Aspirin. To prepare the heating mechanism for the experiment, 250mL of tap water was poured into a 400mL beaker, and this water was then heated on a hot plate to 85⁰C. As the water was heating, the mixture to be heated was concocted. First, 2.595g of salicylic acid was weighed by first tarring a plastic weigh boat on a scale, and then adding the salicylic acid powder-like solid. This amount was then poured into a 125mL Erlenmeyer flask. Next, 5mL of acetic anhydride was measured using a 10mL graduated cylinder, which was then added to the same Erlenmeyer flask. Lastly, 5 drops of the concentrated sulfuric acid catalyst were added to the Erlenmeyer flask, and this was mixed for 5 seconds using a swirling …show more content…
First, 2 medium-sized test tubes were obtained from the front of the laboratory, cleaned using the basic soap and water, and dried. A pea-sized portion of the product was added to the first test tube, using a clean scapula. The same sized amount of salicylic acid added to the other test tube using a separate clean scapula. Each test tube was then labeled with the contents it contained. 5mL of iron (III) chloride (FeCl3) was then measured in two separate clean graduated cylinders (5mL in each cylinder) and 5mL was added to each test tube. Following the addition, a lighter magenta color resulted in the test tube with the experimental product yield, when compared to the tube containing the salicylic acid, which turned a darker shade of