Animations: The Cardiovascular System
Hemopoiesis
After viewing the animation, answer these questions.
1. Hemopoiesis is the process of blood cell formation, which occurs primarily in the red bone marrow.
2. Hemopoiesis begins with undifferentiated cells called hemocytoblasts.
3. These stem cells give rise to many different cell types that make up the cellular elements of blood.
4. What types of hormones influence the differentiation of the blood stem cells? (CSF’s) Colony Stimulating Factors
5. What are the two lines of cells that differentiate from the hemocytoblast? The myeloid or the Lymphoid cell line.
6. Which groups of cells arise from each of these lines? The …show more content…
List the steps for red blood cell (erythrocyte) production. It begins with stimulation of the myeloid stem cells by CSFs to produce a progenitor cell that gives rise to a proerythroblast. The hormone erythropoietin initiates the erythroblast stage which proerythroblasts are stimulated to form erythroblasts. The erythroblast begins to synthesize hemoglobin and gradually decreases in size, giving rise to a normoblast. At this point the nucleus is ejected from the normoblast resulting in a reticulocyte After the reticulocyte enters the blood stream its organelles degenerate at which point it is considered a mature …show more content…
Leukopoiesis is the formation of white blood cells.
15. The myeloid cell line gives rise to granulocytes (eosinophils, basophils and neutrophils) and monocytes.
16. The lymphoid cell line produces lymphocytes.
17. Eosinophilic myelocytes differentiate into eosinophils.
18. Basophilic myelocytes differentiate into basophils.
19. Neutrophilic myelocytes develop into nutrophils.
20. Monocytes are derived from granulocyte stem cells.
21. Lymphocytes are derived from lymphoid stem cell.
22. The two types of lymphocytes that develop are B- and T- lymphocytes.
Hemoglobin Breakdown
After viewing the animation, answer these questions.
1. What happens to the hemoglobin released by the rupture of old red blood cells? It is ingested by macrophages.
2. The globin chains are broken down to individual amino acids that are metabolized or used to build new proteins.
3. What is released from the heme? Iron
4. The remaining structure of the heme goes through a two-step process, being converted to the following two products sequentially biliverdin, which is then converted into biliruben.
5. What plasma protein transports the iron?