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Acquired Immune Deficiency Syndrome Essay

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Acquired Immune Deficiency Syndrome Essay
Acquired immune deficiency syndrome, or AIDS, is a recently recognized disease. It is caused by infection with the human immunodeficiency virus (HIV), which attacks selected cells in the IMMUNE SYSTEM and produces defects in function. These defects may not be apparent for years. They lead, however, to a severe suppression of the immune system 's ability to resist harmful organisms. This leaves the body open to invasion by various infections, which are therefore called opportunistic diseases, and to the development of unusual cancers. The virus also tends to reach certain brain cells. This leads to so-called neuropsychiatric abnormalities, or psychological disturbances caused by physical damage to nerve cells. Since the first AIDS cases were reported in 1981, through mid-1994 more than 402,000 AIDS cases and more than 241,000 deaths have been reported in the United States alone. This is only the tip of the iceberg of HIV infection, however. It is estimated that nearly 1 million Americans had been infected with the virus through the mid-1990s but had not yet developed clinical symptoms. In addition, although the vast majority of documented cases have occurred in the United States, AIDS cases have also been reported in almost every country in the world. Sub-Saharan Africa in particular appears to suffer a heavy burden of this illness. No cure or vaccine now exists for AIDS. Many of those infected with HIV may not even be aware that they carry and can spread the virus. Combating it is a major challenge to biomedical scientists and health-care providers. HIV infection and AIDS represent among the most pressing public-policy and public-health problems worldwide. Definition of AIDS The U.S. CENTERS FOR DISEASE CONTROL AND PREVENTION has established criteria for defining cases of AIDS that are based on laboratory evidence such as T4 cell count, the presence of certain opportunistic diseases, and a range of other conditions. The opportunistic diseases are generally the most


Bibliography: Alcamo, I. E., AIDS: The Biological Basis (1993); Corea, G., The Invisible Epidemic: The Story of Women and AIDS (1992); DeVita, V. T., Jr., AIDS, 3d ed. (1992); Feldman, W. H., et al., eds., The AIDS Directory (1993); Gostin, L. O., AIDS and the Healthcare System (1990); Graubard, S. R., ed., Living with AIDS (1990); Hubley, J., The AIDS Handbook (1990); Mann, J., et al., eds., AIDS in the World, 1992 (1992); McKenzie, N. F., ed., The AIDS Reader (1991); Shilts, R., And the Band Played On (1993); Walker, R. S., AIDS Today, Tomorrow (1991).

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