There is no insulin in her blood which means her muscle cells and other cells in her body are not able to use glucose in respiration as an energy source. Her body signals the breakdown of fats to provide energy in a process called gluconeogenesis. This breakdown of fats produces ketones such as acetone, these molecules are acidic. A build-up of acetone and acetoacetate in Roberta’s blood lowers the pH of her blood. This is known as ketoacidosis. She will begin to rapidly breathe in order to compensate for the high levels of acetone and low pH of her blood.
2. She feels very thirsty despite drinking lots of water.
This is a common symptom of diabetes, another term for this is polydipsia. Roberta feels very …show more content…
Since there is no insulin to transport glucose from the blood stream into cells of tissues, her body is breaking down fats to meet the demand for energy of her muscles and other cells. Gluconeogenesis results in the production of ketones such as acetone and acetoacetate. Ketones are acidic and volatile, as the concentration of ketones in the blood rises, there is a decrease in blood pH to 7.28 in Roberta’s case, (optimum blood pH 7.35) and the blood becomes an acidic environment. Her breath smells of acetone because ketones are volatile compounds. In order to get rid of the acetones in her respiratory system her breathing rate will increase, and ketones evaporate from her breath. The acidic environment of her blood is not suitable for the enzymes and proteins such as haemoglobin, in order to compensate for this her breathing becomes more rapid and deep. This rapid breathing increases the level of oxygen in the blood, and concentration of ketones such as acetone decrease over time, restoring the bloods pH for a …show more content…
A high result indicates that a high percentage of glucose is bound to haemoglobin and has not been metabolised. Somebody at risk would have a percentage of above 8%.This indicates a higher risk of hyperglycaemia and so the patient has not controlled their blood sugar levels properly. Since a diabetic patient’s body is not able to uptake glucose and reset high blood glucose levels back to normal immediately, they need to be cautious with the amount of sugar present in their diet.
The lifespan of a red blood cell is 120 days and the glycation of haemoglobin takes 90-120 days, if the percentage of glycated haemoglobin is higher than 8% it means that there is a high concentration of glucose in the blood which is unhealthy.
According to an article by the American Diabetes Association in January 2006, a glycated haemoglobin percentage of less than 6% shows excellent degree of control and this corresponds to an average blood glucose concentration of 135mg/dL compared to a normal person’s blood glucose concentration which is 79.2 mg/dL to 110 mg/dL. A percentage of 9% shows fair degree of control and greater than 12% indicates extremely poor degree of control of blood glucose